Cargando…

Directed differentiation of hPSCs through a simplified lateral plate mesoderm protocol for generation of articular cartilage progenitors

Developmentally, the articular joints are derived from lateral plate (LP) mesoderm. However, no study has produced both LP derived prechondrocytes and preosteoblasts from human pluripotent stem cells (hPSC) through a common progenitor in a chemically defined manner. Differentiation of hPSCs through...

Descripción completa

Detalles Bibliográficos
Autores principales:	Smith, Christopher A., Humphreys, Paul A., Naven, Mark A., Woods, Steven, Mancini, Fabrizio E., O’Flaherty, Julieta, Meng, Qing-Jun, Kimber, Susan J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882893/ https://www.ncbi.nlm.nih.gov/pubmed/36706111 http://dx.doi.org/10.1371/journal.pone.0280024

Ejemplares similares

Endothelial and hematopoietic hPSCs differentiation via a hematoendothelial progenitor
por: Vargas-Valderrama, Alejandra, et al.
Publicado: (2022)

SIX1(+)PAX3(+) identify a progenitor for myogenic lineage commitment from hPSCs
por: Jaime, Olga G., et al.
Publicado: (2023)

PINE-TREE enables efficient enrichment of prime-edited hPSCs
por: Jia, Mary S., et al.
Publicado: (2023)

Maintenance of hPSCs under Xeno-Free and Chemically Defined Culture Conditions
por: Lim, Jung Jin, et al.
Publicado: (2019)

Generation of functional posterior spinal motor neurons from hPSCs-derived human spinal cord neural progenitor cells
por: Xu, He Jax, et al.
Publicado: (2023)

Generation of caudal-type serotonin neurons and hindbrain-fate organoids from hPSCs
por: Valiulahi, Parvin, et al.
Publicado: (2021)

Defective insulin receptor signaling in hPSCs skews pluripotency and negatively perturbs neural differentiation
por: Teo, Adrian Kee Keong, et al.
Publicado: (2021)

Comparative evaluation of isogenic mesodermal and ectomesodermal chondrocytes from human iPSCs for cartilage regeneration
por: Lee, Ming-Song, et al.
Publicado: (2021)

Precisely controlling endogenous protein dosage in hPSCs and derivatives to model FOXG1 syndrome
por: Zhu, Wenliang, et al.
Publicado: (2019)

Genome Editing and Directed Differentiation of hPSCs for Interrogating Lineage Determinants in Human Pancreatic Development
por: Shi, Zhong-Dong, et al.
Publicado: (2017)

Generation of Schwann cell derived melanocytes from hPSCs identifies pro-metastatic factors in melanoma
por: Samuel, Ryan M., et al.
Publicado: (2023)

Mapping germ-layer specification preventing genes in hPSCs via genome-scale CRISPR screening
por: Xu, Xiangjie, et al.
Publicado: (2020)

Effective derivation of ventricular cardiomyocytes from hPSCs using ascorbic acid-containing maturation medium
por: Kim, Ji-eun, et al.
Publicado: (2023)

Single-cell qPCR facilitates the optimization of hematopoietic differentiation in hPSCs/OP9 coculture system
por: Chen, Haide, et al.
Publicado: (2018)

Protocol for genome-scale CRISPR screening in engineered lineage reporter hPSCs to study cell fate determination
por: Zhou, Zhongshu, et al.
Publicado: (2021)

The lateral plate mesoderm
por: Prummel, Karin D., et al.
Publicado: (2020)

Optimized inducible shRNA and CRISPR/Cas9 platforms for in vitro studies of human development using hPSCs
por: Bertero, Alessandro, et al.
Publicado: (2016)

MSX2 Initiates and Accelerates Mesenchymal Stem/Stromal Cell Specification of hPSCs by Regulating TWIST1 and PRAME
por: Zhang, Leisheng, et al.
Publicado: (2018)

De-erosion of X chromosome dosage compensation by the editing of XIST regulatory regions restores the differentiation potential in hPSCs
por: Motosugi, Nami, et al.
Publicado: (2022)

Rapid induction and long-term self-renewal of neural crest-derived ectodermal chondrogenic cells from hPSCs
por: Shen, Pei, et al.
Publicado: (2022)

A Review of the Role of Bioreactors for iPSCs-Based Tissue-Engineered Articular Cartilage
por: Reina-Mahecha, Alejandro, et al.
Publicado: (2023)

Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition
por: Ordovás, Laura, et al.
Publicado: (2015)

Top-Down Inhibition of BMP Signaling Enables Robust Induction of hPSCs Into Neural Crest in Fully Defined, Xeno-free Conditions
por: Hackland, James O.S., et al.
Publicado: (2017)

Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition
por: Ordovás, Laura, et al.
Publicado: (2018)

miRNA-Based Rapid Differentiation of Purified Neurons from hPSCs Advancestowards Quick Screening for Neuronal Disease Phenotypes In Vitro
por: Ishikawa, Mitsuru, et al.
Publicado: (2020)

Loss of KMT2C reprograms the epigenomic landscape in hPSCs resulting in NODAL overexpression and a failure of hemogenic endothelium specification
por: Maurya, Shailendra, et al.
Publicado: (2021)

ESRG is critical to maintain the cell survival and self-renewal/pluripotency of hPSCs by collaborating with MCM2 to suppress p53 pathway
por: Li, Shasha, et al.
Publicado: (2023)

Standardization of Cell Culture Conditions and Routine Genomic Screening under a Quality Management System Leads to Reduced Genomic Instability in hPSCs
por: Molina-Ruiz, Francisco J., et al.
Publicado: (2022)

Loss of Grem1-articular cartilage progenitor cells causes osteoarthritis
por: Ng, Jia Q., et al.
Publicado: (2023)

Development of human cartilage circadian rhythm in a stem cell-chondrogenesis model
por: Naven, Mark A, et al.
Publicado: (2022)

Fli (+) etsrp (+) Hemato-Vascular Progenitor Cells Proliferate at the Lateral Plate Mesoderm during Vasculogenesis in Zebrafish
por: Chun, Chang Zoon, et al.
Publicado: (2011)

NFATc1 marks articular cartilage progenitors and negatively determines articular chondrocyte differentiation
por: Zhang, Fan, et al.
Publicado: (2023)

Symmetry Breaking of Human Pluripotent Stem Cells (hPSCs) in Micropattern Generates a Polarized Spinal Cord‐Like Organoid (pSCO) with Dorsoventral Organization
por: Seo, Kyubin, et al.
Publicado: (2023)

The clinical potential of articular cartilage-derived progenitor cells: a systematic review
por: Rikkers, Margot, et al.
Publicado: (2022)

Early patterning and specification of cardiac progenitors in gastrulating mesoderm
por: Devine, W Patrick, et al.
Publicado: (2014)

Articular cartilage and changes in Arthritis: Collagen of articular cartilage
por: Eyre, David
Publicado: (2002)

Human Adipose-Derived Mesenchymal Progenitor Cells Engraft into Rabbit Articular Cartilage
por: Wang, Wen, et al.
Publicado: (2015)

Regeneration of Articular Cartilage in Lizard Knee from Resident Stem/Progenitor Cells
por: Alibardi, Lorenzo
Publicado: (2015)

Adult Prg4(+) progenitors repair long-term articular cartilage wounds in vivo
por: Massengale, Mei, et al.
Publicado: (2023)

Neural-mesodermal progenitor interactions in pattern formation: an introduction to the collection
por: Kalcheim, Chaya, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_ve29382qdntaa5kau7t9f75car