Combined modelling of mRNA decay dynamics and single-molecule imaging in the Drosophila embryo uncovers a role for P-bodies in 5′ to 3′ degradation

Regulation of mRNA degradation is critical for a diverse array of cellular processes and developmental cell fate decisions. Many methods for determining mRNA half-lives rely on transcriptional inhibition or metabolic labelling. Here, we use a non-invasive method for estimating half-lives for hundred...

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Detalles Bibliográficos
Autores principales: Forbes Beadle, Lauren, Love, Jennifer C., Shapovalova, Yuliya, Artemev, Artem, Rattray, Magnus, Ashe, Hilary L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882958/
https://www.ncbi.nlm.nih.gov/pubmed/36649329
http://dx.doi.org/10.1371/journal.pbio.3001956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882958/
https://www.ncbi.nlm.nih.gov/pubmed/36649329
http://dx.doi.org/10.1371/journal.pbio.3001956

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