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Displaying and delivering viral membrane antigens via WW domain–activated extracellular vesicles

Membrane proteins expressed on the surface of enveloped viruses are conformational antigens readily recognized by B cells of the immune system. An effective vaccine would require the synthesis and delivery of these native conformational antigens in lipid membranes that preserve specific epitope stru...

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Detalles Bibliográficos
Autores principales: Choi, Sengjin, Yang, Zhiping, Wang, Qiyu, Qiao, Zhi, Sun, Maoyun, Wiggins, Joshua, Xiang, Shi-Hua, Lu, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882979/
https://www.ncbi.nlm.nih.gov/pubmed/36706192
http://dx.doi.org/10.1126/sciadv.ade2708