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Collective fusion activity determines neurotropism of an en bloc transmitted enveloped virus

Measles virus (MeV), which is usually non-neurotropic, sometimes persists in the brain and causes subacute sclerosing panencephalitis (SSPE) several years after acute infection, serving as a model for persistent viral infections. The persisting MeVs have hyperfusogenic mutant fusion (F) proteins tha...

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Detalles Bibliográficos
Autores principales: Shirogane, Yuta, Harada, Hidetaka, Hirai, Yuichi, Takemoto, Ryuichi, Suzuki, Tateki, Hashiguchi, Takao, Yanagi, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882980/
https://www.ncbi.nlm.nih.gov/pubmed/36706187
http://dx.doi.org/10.1126/sciadv.adf3731