Gelsolin inhibits autophagy by regulating actin depolymerization in pancreatic ductal epithelial cells in acute pancreatitis

Gelsolin (GSN) can sever actin filaments associated with autophagy. This study investigated how GSN-regulated actin filaments control autophagy in pancreatic ductal epithelial cells (PDECs) in acute pancreatitis (AP). AP was produced in a rat model and PDECs using caerulein (CAE). Rat pancreatic duc...

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Detalles Bibliográficos
Autores principales: Yang, Huiying, Liang, Zhihai, Xie, Jinlian, Wu, Qing, Qin, Yingying, Zhang, Shiyu, Tang, Guodu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883008/
https://www.ncbi.nlm.nih.gov/pubmed/36722658
http://dx.doi.org/10.1590/1414-431X2023e12279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883008/
https://www.ncbi.nlm.nih.gov/pubmed/36722658
http://dx.doi.org/10.1590/1414-431X2023e12279

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