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Phenome-wide Mendelian randomisation analysis identifies causal factors for age-related macular degeneration

BACKGROUND: Age-related macular degeneration (AMD) is a leading cause of blindness in the industrialised world and is projected to affect >280 million people worldwide by 2040. Aiming to identify causal factors and potential therapeutic targets for this common condition, we designed and undertook...

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Detalles Bibliográficos
Autores principales: Julian, Thomas H, Cooper-Knock, Johnathan, MacGregor, Stuart, Guo, Hui, Aslam, Tariq, Sanderson, Eleanor, Black, Graeme CM, Sergouniotis, Panagiotis I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883012/
https://www.ncbi.nlm.nih.gov/pubmed/36705323
http://dx.doi.org/10.7554/eLife.82546