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Mechanism of Ca(2+) transport by ferroportin

Ferroportin (Fpn) is a transporter that releases ferrous ion (Fe(2+)) from cells and is important for homeostasis of iron in circulation. Export of one Fe(2+) by Fpn is coupled to import of two H(+) to maintain charge balance. Here, we show that human Fpn (HsFpn) binds to and mediates Ca(2+) transpo...

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Detalles Bibliográficos
Autores principales: Shen, Jiemin, Wilbon, Azaan Saalim, Zhou, Ming, Pan, Yaping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883014/
https://www.ncbi.nlm.nih.gov/pubmed/36648329
http://dx.doi.org/10.7554/eLife.82947