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In Silico discovery of aptamers with an enhanced library design strategy

With advances in force fields and algorithms, robust tools have been developed for molecular simulation of three-dimensional structures of nucleic acids and investigation of aptamer-target interactions. The traditional aptamer discovery technique, Systematic Evolution of Ligands by EXponential enric...

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Detalles Bibliográficos
Autores principales: Chen, Long, Zhang, Bibi, Wu, Zengrui, Liu, Guixia, Li, Weihua, Tang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883144/
https://www.ncbi.nlm.nih.gov/pubmed/36733700
http://dx.doi.org/10.1016/j.csbj.2023.01.002