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Identification and interrogation of the gene regulatory network of CEBPA-double mutant acute myeloid leukemia
Acute myeloid leukemia (AML) is a heterogeneous hematological malignancy caused by mutations in genes encoding transcriptional and epigenetic regulators together with signaling genes. It is characterized by a disturbance of differentiation and abnormal proliferation of hematopoietic progenitors. We...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883165/ https://www.ncbi.nlm.nih.gov/pubmed/36333583 http://dx.doi.org/10.1038/s41375-022-01744-5 |