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Identification and interrogation of the gene regulatory network of CEBPA-double mutant acute myeloid leukemia

Acute myeloid leukemia (AML) is a heterogeneous hematological malignancy caused by mutations in genes encoding transcriptional and epigenetic regulators together with signaling genes. It is characterized by a disturbance of differentiation and abnormal proliferation of hematopoietic progenitors. We...

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Detalles Bibliográficos
Autores principales: Adamo, Assunta, Chin, Paulynn, Keane, Peter, Assi, Salam A., Potluri, Sandeep, Kellaway, Sophie G., Coleman, Daniel, Ames, Luke, Ptasinska, Anetta, Delwel, H. Ruud, Cockerill, Peter N., Bonifer, Constanze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883165/
https://www.ncbi.nlm.nih.gov/pubmed/36333583
http://dx.doi.org/10.1038/s41375-022-01744-5