A pro B cell population forms the apex of the leukemic hierarchy in Hoxa9/Meis1-dependent AML

Relapse is a major challenge to therapeutic success in acute myeloid leukemia (AML) and can be partly associated with heterogeneous leukemic stem cell (LSC) properties. In the murine Hoxa9/Meis1-dependent (H9M) AML model, LSC potential lies in three defined immunophenotypes, including Lin(−)cKit(+)...

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Detalles Bibliográficos
Autores principales: Lieske, Anna, Agyeman-Duah, Eric, Selich, Anton, Dörpmund, Nicole, Talbot, Steven R., Schambach, Axel, Maetzig, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883166/
https://www.ncbi.nlm.nih.gov/pubmed/36517672
http://dx.doi.org/10.1038/s41375-022-01775-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883166/
https://www.ncbi.nlm.nih.gov/pubmed/36517672
http://dx.doi.org/10.1038/s41375-022-01775-y

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