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Insulin secretion assays in an engineered MIN6 cell line

Insulin secretion from pancreatic beta cells is crucial for maintaining glucose homeostasis. The murine insulinoma derived MIN6 cell line is commonly used as a model for insulin secretion studies. However, its glucose responsiveness wanes with passaging, and insulin secretion is traditionally measur...

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Detalles Bibliográficos
Autores principales: Yang, Liu, Chen, Wenbiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883224/
https://www.ncbi.nlm.nih.gov/pubmed/36718202
http://dx.doi.org/10.1016/j.mex.2023.102029