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SOCS2-enhanced ubiquitination of SLC7A11 promotes ferroptosis and radiosensitization in hepatocellular carcinoma

Radioresistance is a principal culprit for the failure of radiotherapy in hepatocellular carcinoma (HCC). Insights on the regulation genes of radioresistance and underlying mechanisms in HCC are awaiting for profound investigation. In this study, the suppressor of cytokine signaling 2 (SOCS2) were s...

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Detalles Bibliográficos
Autores principales: Chen, Qianping, Zheng, Wang, Guan, Jian, Liu, Hongxia, Dan, Yao, Zhu, Lin, Song, Yimeng, Zhou, Yuchuan, Zhao, Xinrui, Zhang, Yuhong, Bai, Yang, Pan, Yan, Zhang, Jianghong, Shao, Chunlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883449/
https://www.ncbi.nlm.nih.gov/pubmed/35995846
http://dx.doi.org/10.1038/s41418-022-01051-7