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A self-amplifying USP14-TAZ loop drives the progression and liver metastasis of pancreatic ductal adenocarcinoma

With a 5-year survival rate of approximately 10%, pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal solid malignancies in humans. A poor understanding of the underlying biology has resulted in a lack of effective targeted therapeutic strategies. Tissue microarray and bioinformatics a...

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Detalles Bibliográficos
Autores principales: Zhao, Chunle, Gong, Jun, Bai, Yu, Yin, Taoyuan, Zhou, Min, Pan, Shutao, Liu, Yuhui, Gao, Yang, Zhang, Zhenxiong, Shi, Yongkang, Zhu, Feng, Zhang, Hang, Wang, Min, Qin, Renyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883464/
https://www.ncbi.nlm.nih.gov/pubmed/35906484
http://dx.doi.org/10.1038/s41418-022-01040-w