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Exploration driven by a medial preoptic circuit facilitates fear extinction in mice

Repetitive exposure to fear-associated targets is a typical treatment for patients with panic or post-traumatic stress disorder (PTSD). The success of exposure therapy depends on the active exploration of a fear-eliciting target despite an innate drive to avoid it. Here, we found that a circuit runn...

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Detalles Bibliográficos
Autores principales: Shin, Anna, Ryoo, Jia, Shin, Kwanhoo, Lee, Junesu, Bae, Seohui, Kim, Dae‐Gun, Park, Sae-Geun, Kim, Daesoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883483/
https://www.ncbi.nlm.nih.gov/pubmed/36707677
http://dx.doi.org/10.1038/s42003-023-04442-9