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Pathologically high intraocular pressure disturbs normal iron homeostasis and leads to retinal ganglion cell ferroptosis in glaucoma

Glaucoma can result in retinal ganglion cell (RGC) death and permanently damaged vision. Pathologically high intraocular pressure (ph-IOP) is the leading cause of damaged vision during glaucoma; however, controlling ph-IOP alone does not entirely prevent the loss of glaucomatous RGCs, and the underl...

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Detalles Bibliográficos
Autores principales: Yao, Fei, Peng, Jingjie, Zhang, Endong, Ji, Dan, Gao, Zhaolin, Tang, Yixiong, Yao, Xueyan, Xia, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883496/
https://www.ncbi.nlm.nih.gov/pubmed/35933500
http://dx.doi.org/10.1038/s41418-022-01046-4