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Pathologically high intraocular pressure disturbs normal iron homeostasis and leads to retinal ganglion cell ferroptosis in glaucoma
Glaucoma can result in retinal ganglion cell (RGC) death and permanently damaged vision. Pathologically high intraocular pressure (ph-IOP) is the leading cause of damaged vision during glaucoma; however, controlling ph-IOP alone does not entirely prevent the loss of glaucomatous RGCs, and the underl...
Autores principales: | Yao, Fei, Peng, Jingjie, Zhang, Endong, Ji, Dan, Gao, Zhaolin, Tang, Yixiong, Yao, Xueyan, Xia, Xiaobo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883496/ https://www.ncbi.nlm.nih.gov/pubmed/35933500 http://dx.doi.org/10.1038/s41418-022-01046-4 |
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