TLR4 and MD2 variation among horses with differential TNFα baseline concentrations and response to intravenous lipopolysaccharide infusion

Gram-negative bacterial septicemia is mediated through binding of lipopolysaccharide (LPS) to mammalian toll-like receptor protein 4 (TLR4). TLR4 and its cognate protein, myeloid differentiation factor 2 (MD2) form a heterodimeric complex after binding LPS. This complex induces a cascade of reaction...

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Detalles Bibliográficos
Autores principales: Mukhopadhyay, Abhijit, Cook, Shawna R., SanMiguel, Phillip, Ekenstedt, Kari J., Taylor, Sandra D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883502/
https://www.ncbi.nlm.nih.gov/pubmed/36707633
http://dx.doi.org/10.1038/s41598-023-27956-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883502/
https://www.ncbi.nlm.nih.gov/pubmed/36707633
http://dx.doi.org/10.1038/s41598-023-27956-y

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