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TLR4 and MD2 variation among horses with differential TNFα baseline concentrations and response to intravenous lipopolysaccharide infusion
Gram-negative bacterial septicemia is mediated through binding of lipopolysaccharide (LPS) to mammalian toll-like receptor protein 4 (TLR4). TLR4 and its cognate protein, myeloid differentiation factor 2 (MD2) form a heterodimeric complex after binding LPS. This complex induces a cascade of reaction...
Autores principales: | Mukhopadhyay, Abhijit, Cook, Shawna R., SanMiguel, Phillip, Ekenstedt, Kari J., Taylor, Sandra D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883502/ https://www.ncbi.nlm.nih.gov/pubmed/36707633 http://dx.doi.org/10.1038/s41598-023-27956-y |
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