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Cellular senescence in malignant cells promotes tumor progression in mouse and patient Glioblastoma

Glioblastoma (GBM) is the most common primary malignant brain tumor in adults, yet it remains refractory to systemic therapy. Elimination of senescent cells has emerged as a promising new treatment approach against cancer. Here, we investigated the contribution of senescent cells to GBM progression....

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Detalles Bibliográficos
Autores principales: Salam, Rana, Saliou, Alexa, Bielle, Franck, Bertrand, Mathilde, Antoniewski, Christophe, Carpentier, Catherine, Alentorn, Agusti, Capelle, Laurent, Sanson, Marc, Huillard, Emmanuelle, Bellenger, Léa, Guégan, Justine, Le Roux, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883514/
https://www.ncbi.nlm.nih.gov/pubmed/36707509
http://dx.doi.org/10.1038/s41467-023-36124-9