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Investigation of genetic variants and causal biomarkers associated with brain aging

Delta age is a biomarker of brain aging that captures differences between the chronological age and the predicted biological brain age. Using multimodal data of brain MRI, genomics, and blood-based biomarkers and metabolomics in UK Biobank, this study investigates an explainable and causal basis of...

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Detalles Bibliográficos
Autores principales: Kim, Jangho, Lee, Junhyeong, Nam, Kisung, Lee, Seunggeun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883521/
https://www.ncbi.nlm.nih.gov/pubmed/36707530
http://dx.doi.org/10.1038/s41598-023-27903-x