Physiologically-based pharmacokinetic modeling to predict drug-drug interactions of dabigatran etexilate and rivaroxaban in the Chinese older adults

INTRODUCTION: Drug-drug interaction (DDI) is one of the major concerns for the clinical use of NOACs in the older adults considering that coexistence of multiple diseases and comorbidity were common. Current guidelines on the DDI management were established based on clinical studies conducted in hea...

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Detalles Bibliográficos
Autores principales: Sia, Jie En Valerie, Lai, Xuan, Wu, Xinyi, Zhang, Fan, Li, Haiyan, Cui, Cheng, Liu, Dongyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science B.V 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883662/
https://www.ncbi.nlm.nih.gov/pubmed/36626944
http://dx.doi.org/10.1016/j.ejps.2023.106376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883662/
https://www.ncbi.nlm.nih.gov/pubmed/36626944
http://dx.doi.org/10.1016/j.ejps.2023.106376

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