Fatty acids negatively regulate platelet function through formation of noncanonical 15‐lipoxygenase‐derived eicosanoids

The antiplatelet effect of polyunsaturated fatty acids is primarily attributed to its metabolism to bioactive metabolites by oxygenases, such as lipoxygenases (LOX). Platelets have demonstrated the ability to generate 15‐LOX‐derived metabolites (15‐oxylipins); however, whether 15‐LOX is in the plate...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Adriana, van Hoorebeke, Christopher, Tourdot, Benjamin E., Perry, Steven C., Lee, Grace, Rhoads, Nicole, Rickenberg, Andrew, Green, Abigail R., Sorrentino, James, Yeung, Jennifer, Freedman, J. Cody, Holman, Theodore R., Holinstat, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883682/
https://www.ncbi.nlm.nih.gov/pubmed/36708179
http://dx.doi.org/10.1002/prp2.1056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883682/
https://www.ncbi.nlm.nih.gov/pubmed/36708179
http://dx.doi.org/10.1002/prp2.1056

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