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Fatty acids negatively regulate platelet function through formation of noncanonical 15‐lipoxygenase‐derived eicosanoids
The antiplatelet effect of polyunsaturated fatty acids is primarily attributed to its metabolism to bioactive metabolites by oxygenases, such as lipoxygenases (LOX). Platelets have demonstrated the ability to generate 15‐LOX‐derived metabolites (15‐oxylipins); however, whether 15‐LOX is in the plate...
Autores principales: | Yamaguchi, Adriana, van Hoorebeke, Christopher, Tourdot, Benjamin E., Perry, Steven C., Lee, Grace, Rhoads, Nicole, Rickenberg, Andrew, Green, Abigail R., Sorrentino, James, Yeung, Jennifer, Freedman, J. Cody, Holman, Theodore R., Holinstat, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883682/ https://www.ncbi.nlm.nih.gov/pubmed/36708179 http://dx.doi.org/10.1002/prp2.1056 |
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