ISoLDE: a data-driven statistical method for the inference of allelic imbalance in datasets with reciprocal crosses

MOTIVATION: Allelic imbalance (AI), i.e. the unequal expression of the alleles of the same gene in a single cell, affects a subset of genes in diploid organisms. One prominent example of AI is parental genomic imprinting, which results in parent-of-origin-dependent, mono-allelic expression of a limi...

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Detalles Bibliográficos
Autores principales: Reynès, Christelle, Kister, Guilhem, Rohmer, Marine, Bouschet, Tristan, Varrault, Annie, Dubois, Emeric, Rialle, Stéphanie, Journot, Laurent, Sabatier, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883709/
https://www.ncbi.nlm.nih.gov/pubmed/31350542
http://dx.doi.org/10.1093/bioinformatics/btz564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883709/
https://www.ncbi.nlm.nih.gov/pubmed/31350542
http://dx.doi.org/10.1093/bioinformatics/btz564

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