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ISoLDE: a data-driven statistical method for the inference of allelic imbalance in datasets with reciprocal crosses
MOTIVATION: Allelic imbalance (AI), i.e. the unequal expression of the alleles of the same gene in a single cell, affects a subset of genes in diploid organisms. One prominent example of AI is parental genomic imprinting, which results in parent-of-origin-dependent, mono-allelic expression of a limi...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883709/ https://www.ncbi.nlm.nih.gov/pubmed/31350542 http://dx.doi.org/10.1093/bioinformatics/btz564 |