How sequence alignment scores correspond to probability models

MOTIVATION: Sequence alignment remains fundamental in bioinformatics. Pair-wise alignment is traditionally based on ad hoc scores for substitutions, insertions and deletions, but can also be based on probability models (pair hidden Markov models: PHMMs). PHMMs enable us to: fit the parameters to eac...

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Detalles Bibliográficos
Autor principal: Frith, Martin C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883716/
https://www.ncbi.nlm.nih.gov/pubmed/31329241
http://dx.doi.org/10.1093/bioinformatics/btz576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883716/
https://www.ncbi.nlm.nih.gov/pubmed/31329241
http://dx.doi.org/10.1093/bioinformatics/btz576

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