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How sequence alignment scores correspond to probability models
MOTIVATION: Sequence alignment remains fundamental in bioinformatics. Pair-wise alignment is traditionally based on ad hoc scores for substitutions, insertions and deletions, but can also be based on probability models (pair hidden Markov models: PHMMs). PHMMs enable us to: fit the parameters to eac...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883716/ https://www.ncbi.nlm.nih.gov/pubmed/31329241 http://dx.doi.org/10.1093/bioinformatics/btz576 |