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Efficient parameterization of large-scale dynamic models based on relative measurements

MOTIVATION: Mechanistic models of biochemical reaction networks facilitate the quantitative understanding of biological processes and the integration of heterogeneous datasets. However, some biological processes require the consideration of comprehensive reaction networks and therefore large-scale m...

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Detalles Bibliográficos
Autores principales: Schmiester, Leonard, Schälte, Yannik, Fröhlich, Fabian, Hasenauer, Jan, Weindl, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883733/
https://www.ncbi.nlm.nih.gov/pubmed/31347657
http://dx.doi.org/10.1093/bioinformatics/btz581