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Activation of autophagy inhibits the activation of NLRP3 inflammasome and alleviates sevoflurane-induced cognitive dysfunction in elderly rats

AIMS/INTRODUCTION: As a common complication in elderly patients after surgery/anesthesia, postoperative cognitive dysfunction (POCD) is mainly characterized by memory, attention, motor, and intellectual retardation. Neuroinflammation is one of the most uncontroversial views in POCD. The sevoflurane-...

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Detalles Bibliográficos
Autores principales: Zhou, Junjie, Zhang, Chao, Fang, Xu, Zhang, Naixin, Zhang, Xiaoxi, Zhu, Zhaoqiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883890/
https://www.ncbi.nlm.nih.gov/pubmed/36709248
http://dx.doi.org/10.1186/s12868-023-00777-5