Cargando…
Altered dynamics of glymphatic flow in a mature-onset Tet-off APP mouse model of amyloidosis
BACKGROUND: Alzheimer’s disease (AD) is an incurable neurodegenerative disorder characterised by the progressive buildup of toxic amyloid-beta (Aβ) and tau protein aggregates eventually leading to cognitive decline. Recent lines of evidence suggest that an impairment of the glymphatic system (GS), a...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883946/ https://www.ncbi.nlm.nih.gov/pubmed/36707887 http://dx.doi.org/10.1186/s13195-023-01175-z |