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Altered dynamics of glymphatic flow in a mature-onset Tet-off APP mouse model of amyloidosis

BACKGROUND: Alzheimer’s disease (AD) is an incurable neurodegenerative disorder characterised by the progressive buildup of toxic amyloid-beta (Aβ) and tau protein aggregates eventually leading to cognitive decline. Recent lines of evidence suggest that an impairment of the glymphatic system (GS), a...

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Detalles Bibliográficos
Autores principales: Ben-Nejma, Inès R. H., Keliris, Aneta J., Vanreusel, Verdi, Ponsaerts, Peter, Van der Linden, Annemie, Keliris, Georgios A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883946/
https://www.ncbi.nlm.nih.gov/pubmed/36707887
http://dx.doi.org/10.1186/s13195-023-01175-z

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