Cargando…

Histone methyltransferase SETD1A interacts with notch and promotes notch transactivation to augment ovarian cancer development

BACKGROUND: High expression of SETD1A, a histone methyltransferase that specifically methylates H3K4, acted as a key oncogene in several human cancers. However, the function and underlying molecular mechanism of SETD1A in ovarian cancer (OV) remain markedly unknown. METHODS: The expression of SETD1A...

Descripción completa

Detalles Bibliográficos
Autores principales: Chai, Hongjuan, Pan, Chunpeng, Zhang, Mingyang, Huo, Haizhong, Shan, Haiyan, Wu, Jugang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883963/
https://www.ncbi.nlm.nih.gov/pubmed/36707804
http://dx.doi.org/10.1186/s12885-023-10573-3