Requirement for STAT3 and its target, TFCP2L1, in self-renewal of naïve pluripotent stem cells in vivo and in vitro

We previously demonstrated gradual loss of epiblast during diapause in embryos lacking components of the LIF/IL6 receptor. Here, we explore the requirement for the downstream signalling transducer andactivator of transcription STAT3 and its target, TFCP2L1, in maintenance of naïve pluripotency. Unli...

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Detalles Bibliográficos
Autores principales: Kraunsoe, Sophie, Azami, Takuya, Pei, Yihan, Martello, Graziano, Jones, Kenneth, Boroviak, Thorsten, Nichols, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884119/
https://www.ncbi.nlm.nih.gov/pubmed/36504370
http://dx.doi.org/10.1242/bio.059650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884119/
https://www.ncbi.nlm.nih.gov/pubmed/36504370
http://dx.doi.org/10.1242/bio.059650

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