Loss of Lactate/Proton Monocarboxylate Transporter 4 Induces Ferroptosis via the AMPK/ACC Pathway and Inhibition of Autophagy on Human Bladder Cancer 5637 Cell Line

BACKGROUND: Ferroptosis and autophagy have an important role in the occurrence and development of cancer, and lactate in cells and microenvironment is one of the influencing factors of ferroptosis and autophagy. The lactate/proton monocarboxylate transporter 4 (MCT4), which is expressed in the cell...

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Detalles Bibliográficos
Autores principales: Dong, Siqi, Zheng, Lei, Jiang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884169/
https://www.ncbi.nlm.nih.gov/pubmed/36718218
http://dx.doi.org/10.1155/2023/2830306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884169/
https://www.ncbi.nlm.nih.gov/pubmed/36718218
http://dx.doi.org/10.1155/2023/2830306

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