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Generation of Gαi knock-out HEK293 cells illuminates Gαi-coupling diversity of GPCRs
G-protein-coupled receptors (GPCRs) are pivotal cell membrane proteins that sense extracellular molecules and activate cellular responses. The G-protein α subunit i (Gαi) family represents the most common GPCR-coupling partner and consists of eight subunits with distinct signaling properties. Howeve...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884212/ https://www.ncbi.nlm.nih.gov/pubmed/36709222 http://dx.doi.org/10.1038/s42003-023-04465-2 |