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Generation of Gαi knock-out HEK293 cells illuminates Gαi-coupling diversity of GPCRs

G-protein-coupled receptors (GPCRs) are pivotal cell membrane proteins that sense extracellular molecules and activate cellular responses. The G-protein α subunit i (Gαi) family represents the most common GPCR-coupling partner and consists of eight subunits with distinct signaling properties. Howeve...

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Detalles Bibliográficos
Autores principales:	Ono, Yuki, Kawakami, Kouki, Nakamura, Gaku, Ishida, Satoru, Aoki, Junken, Inoue, Asuka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884212/ https://www.ncbi.nlm.nih.gov/pubmed/36709222 http://dx.doi.org/10.1038/s42003-023-04465-2

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