Immortalized murine tenocyte cells: a novel and innovative tool for tendon research

Primary tenocytes rapidly undergo senescence and a phenotypic drift upon in vitro monolayer culture, which limits tendon research. The Ink4a/Arf locus encodes the proteins p16(Ink4a/Arf) and p14(ARF) (p19(ARF) in mice) that regulate cell cycle progression and senescence. We here established an immor...

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Detalles Bibliográficos
Autores principales: Oreff, Gil Lola, Maurer, Barbara, ELKhamary, Ahmed N., Gerner, Iris, Sexl, Veronika, Jenner, Florien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884217/
https://www.ncbi.nlm.nih.gov/pubmed/36709227
http://dx.doi.org/10.1038/s41598-023-28318-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884217/
https://www.ncbi.nlm.nih.gov/pubmed/36709227
http://dx.doi.org/10.1038/s41598-023-28318-4

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