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Immortalized murine tenocyte cells: a novel and innovative tool for tendon research
Primary tenocytes rapidly undergo senescence and a phenotypic drift upon in vitro monolayer culture, which limits tendon research. The Ink4a/Arf locus encodes the proteins p16(Ink4a/Arf) and p14(ARF) (p19(ARF) in mice) that regulate cell cycle progression and senescence. We here established an immor...
Autores principales: | Oreff, Gil Lola, Maurer, Barbara, ELKhamary, Ahmed N., Gerner, Iris, Sexl, Veronika, Jenner, Florien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884217/ https://www.ncbi.nlm.nih.gov/pubmed/36709227 http://dx.doi.org/10.1038/s41598-023-28318-4 |
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