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Glutamine increases stability of TPH1 mRNA via p38 mitogen-activated kinase in mouse mastocytoma cells

Expression changes for tryptophan hydroxylase 1 (TPH1), the rate-limiting enzyme in serotonin synthesis, by environmental glutamine (GLN) were examined in mouse mastocytoma-derived P815-HTR cells. GLN-treated cells exhibited a robust increase in TPH1 mRNA after a 6 h exposure to GLN. 6-Diazo-5-oxo-L...

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Detalles Bibliográficos
Autores principales: Park, Heeyoung, Lee, Chang-Wook, Kang, Jieun, Sadra, Ali, Huh, Sung-Oh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884262/
https://www.ncbi.nlm.nih.gov/pubmed/36331742
http://dx.doi.org/10.1007/s11033-022-07693-7