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The RESP AI model accelerates the identification of tight-binding antibodies
High-affinity antibodies are often identified through directed evolution, which may require many iterations of mutagenesis and selection to find an optimal candidate. Deep learning techniques hold the potential to accelerate this process but the existing methods cannot provide the confidence interva...
Autores principales: | Parkinson, Jonathan, Hard, Ryan, Wang, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884274/ https://www.ncbi.nlm.nih.gov/pubmed/36709319 http://dx.doi.org/10.1038/s41467-023-36028-8 |
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