Molecular elucidation of drug-induced abnormal assemblies of the hepatitis B virus capsid protein by solid-state NMR

Hepatitis B virus (HBV) capsid assembly modulators (CAMs) represent a recent class of anti-HBV antivirals. CAMs disturb proper nucleocapsid assembly, by inducing formation of either aberrant assemblies (CAM-A) or of apparently normal but genome-less empty capsids (CAM-E). Classical structural approa...

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Detalles Bibliográficos
Autores principales: Lecoq, Lauriane, Brigandat, Louis, Huber, Rebecca, Fogeron, Marie-Laure, Wang, Shishan, Dujardin, Marie, Briday, Mathilde, Wiegand, Thomas, Callon, Morgane, Malär, Alexander, Durantel, David, Burdette, Dara, Berke, Jan Martin, Meier, Beat H., Nassal, Michael, Böckmann, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884277/
https://www.ncbi.nlm.nih.gov/pubmed/36709212
http://dx.doi.org/10.1038/s41467-023-36219-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884277/
https://www.ncbi.nlm.nih.gov/pubmed/36709212
http://dx.doi.org/10.1038/s41467-023-36219-3

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