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Molecular elucidation of drug-induced abnormal assemblies of the hepatitis B virus capsid protein by solid-state NMR

Hepatitis B virus (HBV) capsid assembly modulators (CAMs) represent a recent class of anti-HBV antivirals. CAMs disturb proper nucleocapsid assembly, by inducing formation of either aberrant assemblies (CAM-A) or of apparently normal but genome-less empty capsids (CAM-E). Classical structural approa...

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Detalles Bibliográficos
Autores principales:	Lecoq, Lauriane, Brigandat, Louis, Huber, Rebecca, Fogeron, Marie-Laure, Wang, Shishan, Dujardin, Marie, Briday, Mathilde, Wiegand, Thomas, Callon, Morgane, Malär, Alexander, Durantel, David, Burdette, Dara, Berke, Jan Martin, Meier, Beat H., Nassal, Michael, Böckmann, Anja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884277/ https://www.ncbi.nlm.nih.gov/pubmed/36709212 http://dx.doi.org/10.1038/s41467-023-36219-3

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