Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions

Multiple trans-synaptic complexes organize synapse development, yet their roles in the mature brain and cooperation remain unclear. We analyzed the postsynaptic adhesion protein LRRTM1 in the prefrontal cortex (PFC), a region relevant to cognition and disorders. LRRTM1 knockout (KO) mice had fewer s...

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Detalles Bibliográficos
Autores principales: de Arce, Karen Perez, Ribic, Adema, Chowdhury, Dhrubajyoti, Watters, Katherine, Thompson, Garth J., Sanganahalli, Basavaraju G., Lippard, Elizabeth T. C., Rohlmann, Astrid, Strittmatter, Stephen M., Missler, Markus, Hyder, Fahmeed, Biederer, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884278/
https://www.ncbi.nlm.nih.gov/pubmed/36709330
http://dx.doi.org/10.1038/s41467-023-36042-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884278/
https://www.ncbi.nlm.nih.gov/pubmed/36709330
http://dx.doi.org/10.1038/s41467-023-36042-w

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