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Charge-voltage curves of Shaker potassium channel are not hysteretic at steady state

Charge-voltage curves of many voltage-gated ion channels exhibit hysteresis but such curves are also a direct measure of free energy of channel gating and, hence, should be path-independent. Here, we identify conditions to measure steady-state charge-voltage curves and show that these are curves are...

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Detalles Bibliográficos
Autores principales: Cowgill, John, Chanda, Baron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884579/
https://www.ncbi.nlm.nih.gov/pubmed/36692860
http://dx.doi.org/10.1085/jgp.202112883