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STAT3 regulates CD8(+) T cell differentiation and functions in cancer and acute infection

In cancer, persistent antigens drive CD8(+) T cell differentiation into exhausted progenitor (T(ex)(prog)) and terminally exhausted (T(ex)(term)) cells. However, how the extrinsic and intrinsic regulatory mechanisms cooperate during this process still remains not well understood. Here, we found that...

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Detalles Bibliográficos
Autores principales: Sun, Qinli, Zhao, Xiaohong, Li, Ruifeng, Liu, Dingfeng, Pan, Birui, Xie, Bowen, Chi, Xinxin, Cai, Dongli, Wei, Peng, Xu, Wei, Wei, Kun, Zhao, Zixuan, Fu, Yujie, Ni, Ling, Dong, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884582/
https://www.ncbi.nlm.nih.gov/pubmed/36688918
http://dx.doi.org/10.1084/jem.20220686