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STAT3 regulates CD8(+) T cell differentiation and functions in cancer and acute infection
In cancer, persistent antigens drive CD8(+) T cell differentiation into exhausted progenitor (T(ex)(prog)) and terminally exhausted (T(ex)(term)) cells. However, how the extrinsic and intrinsic regulatory mechanisms cooperate during this process still remains not well understood. Here, we found that...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884582/ https://www.ncbi.nlm.nih.gov/pubmed/36688918 http://dx.doi.org/10.1084/jem.20220686 |