Immune-interacting lymphatic endothelial subtype at capillary terminals drives lymphatic malformation

Oncogenic mutations in PIK3CA, encoding p110α-PI3K, are a common cause of venous and lymphatic malformations. Vessel type–specific disease pathogenesis is poorly understood, hampering development of efficient therapies. Here, we reveal a new immune-interacting subtype of Ptx3-positive dermal lymphat...

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Detalles Bibliográficos
Autores principales: Petkova, Milena, Kraft, Marle, Stritt, Simon, Martinez-Corral, Ines, Ortsäter, Henrik, Vanlandewijck, Michael, Jakic, Bojana, Baselga, Eulàlia, Castillo, Sandra D., Graupera, Mariona, Betsholtz, Christer, Mäkinen, Taija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884640/
https://www.ncbi.nlm.nih.gov/pubmed/36688917
http://dx.doi.org/10.1084/jem.20220741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884640/
https://www.ncbi.nlm.nih.gov/pubmed/36688917
http://dx.doi.org/10.1084/jem.20220741

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