Efficacy, Safety and Pharmacokinetics of IL-17 Monoclonal Antibody Injection (AK111) in Patients with Moderate-to-Severe Plaque Psoriasis: A Randomized, Double-Blinded, Placebo-Controlled Phase Ib Multidose Escalation Clinical Study

OBJECTIVES: To evaluate the safety, tolerability, immunogenicity, and induced expression of skin biomarkers of AK111 injection after multiple administrations in subjects with moderate-to-severe plaque psoriasis. METHODS: This study is a randomized, double-blinded, placebo-parallel-controlled study u...

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Detalles Bibliográficos
Autores principales: Jiang, Congjun, Zhou, Huan, Zhang, Wanlu, Xia, Yu, Li, Baiyong, Ni, Xiang, Wang, Guoqin, Zhang, Wenhui, Chen, Benchao, He, Zhimei, Zhang, Min, Chen, Rui, Jin, Hongzhong, Deng, Liehua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884719/
https://www.ncbi.nlm.nih.gov/pubmed/36566344
http://dx.doi.org/10.1007/s13555-022-00880-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884719/
https://www.ncbi.nlm.nih.gov/pubmed/36566344
http://dx.doi.org/10.1007/s13555-022-00880-1

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