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Mitochondrial plasticity supports proliferative outgrowth and invasion of ovarian cancer spheroids during adhesion

BACKGROUND: Ovarian cancer cells aggregate during or after exfoliation from the primary tumor to form threedimensional spheroids. Spheroid formation provides a survival advantage during peritoneal dissemination in nutrient and oxygen-depleted conditions which is accompanied by a suppressed metabolic...

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Detalles Bibliográficos
Autores principales: Grieco, Joseph P., Compton, Stephanie L. E., Bano, Nazia, Brookover, Lucy, Nichenko, Anna S., Drake, Joshua C., Schmelz, Eva M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884807/
https://www.ncbi.nlm.nih.gov/pubmed/36727073
http://dx.doi.org/10.3389/fonc.2022.1043670