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TYRO3 blockade enhances anti-PD-1 therapy response by modulating expression of CCN1 in tumor microenvironment

BACKGROUND: Immunological contexture differs across malignancies, and understanding it in the tumor microenvironment (TME) is essential for development of new anticancer agents in order to achieve synergistic effects with anti-programmed cell death protein-1 (PD-1) therapy. TYRO3, AXL, and MERTK rec...

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Detalles Bibliográficos
Autores principales: Park, Miso, Kuen, Da-Sol, Park, Jaewoo, Choi, Munkyung, Kim, Yeonji, Roh, Eun Chae, Choi, Yong June, Kim, Yoon Gyoon, Chung, Yeonseok, Cho, Sung Yun, Kang, Keon Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884874/
https://www.ncbi.nlm.nih.gov/pubmed/36693679
http://dx.doi.org/10.1136/jitc-2022-006084