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TYRO3 blockade enhances anti-PD-1 therapy response by modulating expression of CCN1 in tumor microenvironment
BACKGROUND: Immunological contexture differs across malignancies, and understanding it in the tumor microenvironment (TME) is essential for development of new anticancer agents in order to achieve synergistic effects with anti-programmed cell death protein-1 (PD-1) therapy. TYRO3, AXL, and MERTK rec...
Autores principales: | Park, Miso, Kuen, Da-Sol, Park, Jaewoo, Choi, Munkyung, Kim, Yeonji, Roh, Eun Chae, Choi, Yong June, Kim, Yoon Gyoon, Chung, Yeonseok, Cho, Sung Yun, Kang, Keon Wook |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9884874/ https://www.ncbi.nlm.nih.gov/pubmed/36693679 http://dx.doi.org/10.1136/jitc-2022-006084 |
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